klinefelter syndrome prognosis

eMedTV serves only as an informational resource. [3] The primary features are infertility and small poorly functioning testicles. Chromosomes are packages of genes found in every cell in the body. This may include examining the genital area and chest, performing tests to check reflexes, and assessing development and functioning.The main tests used to diagnose Klinefelter syndrome are: 1. Klinefelter syndrome can be different for different people. We offer support and information to all affected by, or having an interest in, Klinefelter’s Syndrome. « What are common symptoms? To describe mortality in KS, we conducted an epidemiological study, using Danish registers covering the entire nation. For some, the symptoms start early in life and treatment may be needed throughout all stages of growth. Klinefelter syndrome appears to occur more frequently with both older maternal and paternal age (over the age of 35.) The prognosis of Klinefelter syndrome depends on the extent of the condition. Hazard ratios were calculated using Cox regression analysis with stratification, using each KS patient and his matched controls as a stratum. Klinefelter syndrome occurs in about 1 out of 500 to 1,000 baby boys. Ratcliffe, S. (1999). Sometimes, symptoms are more evident and may include weaker muscles, greater height, poor coordination, less body hair, breast … The population frequency is 1: 1000 males. Typically, a person’s genetic code is made up of either two X chromosomes (genetic female) or one X and one Y chromosome (genetic male). These old medical books often paint a rather bleak picture. Rarely people with Klinefelter syndrome can have even more X chromosomes, such as 48 XXXY or 49 XXXXY . Klinefelter syndrome shows a wide phenotypic spectrum, ranging from mild or aspecific (undetected) cases, to sterility, to learning or behavioral problems and/or physical features becoming manifest at an early age. Klinefelter syndrome is a chromosomal condition in boys and men that can affect physical and intellectual development. Klinefelter syndrome is a chromosomal condition in boys and men that can affect physical and intellectual development. La sindrome di Klinefelter è una malattia genetica, cronica, caratterizzata da un'anomalia cromosomica in cui un individuo di sesso maschile possiede un cromosoma X soprannumerario. Klinefelter syndrome occurs when a male has an additional X chromosome, making them 47 XXY.Under normal circumstances males have XY sex chromosomes and females have XX sex chromosomes. Much of the early literature about Klinefelter’s Syndrome (KS) mentions the high proportion of KS males in the prison population and low IQ. It was clinically described for the first time by Kleinfelter in 1942. Klinefelter syndrome (KS), also known as 47,XXY is the set of symptoms that result from two or more X chromosomes in males. Advances in fertility treatments have made it possible for some to father children. Testosterone replacement should protect bone health and induce secondary sex characteristics such as body and facial hair. Klinefelter syndrome can be different for different people. Women who get pregnant after age 35 are slightly more likely to have a boy with Quality of life, limitations and expectatios of someone with Klinefelter Syndrome. When treatments are done early, the severity of some related conditions is significantly reduced. Chromosomes are packages of genes found in every cell in the body. The prognosis for Klinefelter Syndrome Life expectancy in patients with Klinefelter syndrome is near to the average life expectancy and therefore has an overall good prognosis. Klinefelter syndrome is the most common sex chromosome disorder, affecting approximately 1/500 to 1/1000 males. Klinefelter syndrome happens when a male is born with an additional X chromosome. Genetics in Medicine, 5(6), 460-468. Under normal circumstances males have XY sex chromosomes and females have XX sex chromosomes . Males with Klinefelter Syndrome who wish to reproduce can often successfully do so using In-vitro Fertilization techniques. Klinefelter syndrome (sometimes called Klinefelter's, KS or XXY) is where boys and men are born with an extra X chromosome. How would you pronounce Klinefelter Syndrome? Affected boys tend to be tall with disproportionately long arms and legs. Next. Ratcliffe, S. (1999). Their chance of developing these disorders is similar to that of women in the general population. It is sometimes just called XXY. There are not any answers for this question yet. The most common symptom of Klinefelter syndrome is infertility, which often isn't noticed until adulthood. Klinefelter syndrome results when a boy is born with at least 1 extra X chromosome. An individual usually presents with symptoms of Klinefelter syndrome during childhood, puberty or adulthood when infertility becomes an issue. Rarely people with Klinefelter syndrome can have even more X chromosomes, such as 48 XXXY or 49 XXXXY.This is associated with more severe features. Blood or urine samples can reveal abnormal hormone levels that are a sign of Klinefelter syndrome. Hormone testing. Klinefelter syndrome happens when a male is born with an additional X chromosome. Sometimes boys with KS may struggle through adolescence. The extra X chromosome typically affects physical, neurodevelopmental, behavioral, and neurocognitive functioning. They may have Klinefelter syndrome: Expanding the phenotype and identifying new research directions. … The primary features are infertility and small poorly functioning testicles. Most commonly, affected individuals are taller than average are unable to father biological children (infertile); however the signs and symptoms of Klinefelter syndrome vary among boys and men with this condition. Prognosis - The Future - Klinefelter's Syndrome Association : Klinefelter's Syndrome Association Prognosis – The Future Much of the early literature about Klinefelter’s Syndrome (KS) mentions the high proportion of KS males in the prison population and low IQ. Klinefelter syndrome, 47, XXY is a clinical example of sex chromosome lesions. Klinefelter syndrome is a genetic condition affecting males, and it often isn't diagnosed until adulthood.Klinefelter syndrome may adversely affect testicular growth, resulting in smaller than normal testicles, which can lead to lower production of testosterone. All patients underwent clinical evaluation, which included a complete history, physical examination, and measurement of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and total testosterone levels. Some of our members have written about their lives which we hope will change the perception of the abilities of those with KS or XXY. [encyclopedia.com] Etiology Epidemiology Klinefelter syndrome is estimated to affect approximately 1 in 500 male babies and is, therefore, one of the most common chromosomal … Prognosis – The Future Much of the early literature about Klinefelter’s Syndrome (KS) mentions the high proportion of KS males in the prison population and low IQ. Many of those who have KS may not even realise they have the condition as 75% are undiagnosed. Klinefelter syndrome (sometimes called Klinefelter's, KS or XXY) is where boys and men are born with an extra X chromosome. Klinefelter Syndrome with XY/XXY Mosaic (Klinefelter's Syndrome with XY/XXY Mosaic): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis. The syndrome may also cause reduced muscle mass, reduced body and facial hair, and enlarged breast tissue. Physical symptoms of Klinefelter syndrome include: Being born with a smaller penis, and/or undescended testicle (s). 0 answers. Most commonly, affected individuals are taller than average are unable to father biological children (infertile); however the signs and symptoms of Klinefelter syndrome vary among boys and men with this condition. Samples can reveal abnormal hormone levels that are a sign of Klinefelter syndrome happens when a boy born! Taller than their peers and men with Klinefelter syndrome is infertility, which often is n't noticed until.. Some, the severity of some related conditions is significantly reduced additional X chromosome will on! 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